Bridging the Gap—Enabling Technology Providers & the Path to the Clinic
Lonrú is attending the Precision Genome Engineering: Translating the Human Genome to the Clinic meeting in Killarney this week. The meeting brings together the leading minds in gene editing, delivery systems, and therapeutic development to discuss the latest advancements shaping the future of precision medicine. From new CRISPR-based tools and enabling technologies to the challenges of translating innovation into the clinic, the conference highlights the critical steps needed to move from discovery to impact. Our poster presentation yesterday on streamlining preclinical-to-IND pathways generated interest, not just from therapeutic developers, but also from enabling technology providers eager to gain a clearer view of the challenges their partners and customers face in clinical translation.
Why Are Enabling Technology Providers Paying Attention?
While much of the conversation around gene editing focuses on therapeutic breakthroughs, every successful CRISPR-based therapy depends on the enabling technologies that support it—from delivery systems and genome engineering platforms to advanced analytical tools and scalable manufacturing solutions. Many enabling technology providers recognize that to best serve their customers, they need a deeper understanding of:
✔ Regulatory bottlenecks that delay clinical progression and impact product adoption.
✔ Common reasons for IND holds, including safety concerns, CMC issues, and assay validation gaps.
✔ Preclinical validation requirements that define what data therapeutic developers need to move forward.
By better aligning their solutions with these pain points, enabling technology providers can position themselves as indispensable partners in the journey from discovery to the clinic.
Beyond the Poster: Full Report & Decision Trees
Attendees we met with appreciated having access to our full report to dive deeper into the topics covered in the poster. In particular, the decision tree framework resonated with both therapeutic and technology developers, offering a structured approach to mitigating risks early in the development process.
For those who couldn’t attend the poster session—or who want to explore the findings in more detail—you can view and download the full report, poster, and decision trees here:
Lonrú’s full report, poster and decision tree framework are available for download.
The conversation doesn’t end here—if you’re an enabling technology provider looking to bridge the gap between research and clinical success, let’s connect. Lonrú Consulting specializes in strategic insights that help align enabling technologies with the needs of therapeutic developers, ensuring that innovation translates into impact.
